From genetics to gene networks: Gene Network Inference via Structural Equation Modeling in Genetical Genomics Experiments
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Gene network inference via structural equation modeling in genetical genomics experiments.
Our goal is gene network inference in genetical genomics or systems genetics experiments. For species where sequence information is available, we first perform expression quantitative trait locus (eQTL) mapping by jointly utilizing cis-, cis-trans-, and trans-regulation. After using local structural models to identify regulator-target pairs for each eQTL, we construct an encompassing directed n...
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تاریخ انتشار 2007